This paper aims to investigate the factors affecting the performance of 58 real estate business is trading on Ho Chi Minh and Ha Noi stock Exchange through two indicators is return on equity (ROE) and return on assets (ROA). By using multivariate linear regression using ordinary least squares method (OLS) to estimate the, the findings shows that the performance of the real estate business is affected by the ratio of loans / total debt, ratio of fixed assets / total assets, the ratio of fund shares / total equity, cost ratio for sales and business management and uptime of business. From the results of the subject has also proposed a number of measures to improve the performance of the real estate business in the current period