Experiment was conducted under laboratory condion of Can Tho University to evaluate the inhibited ability of fungicides and Bacillus antagonistic bacterium against four fungal pathogens of rice seed collected at SocTrang province. Results showed among six kinds of fungicides that Workup 9SL, Nustar 40EC and Folicur 250EW gave high effect on Fusarium moniliforme, Workup 9SL also high effect on Curvularia lunata and Nustar 40EC on Bipolaris oryzae. Man 80WP gave low effect on four fungi. Among three kinds of Bacillus e.i AGB4 (Bacillus sp.), AGB17 (Bacillus pumilus) and AGB27 (Bacillus megaterium) showed that AGB4 and AGB17 had good effect on Curvularia lunata, Bipolaris oryzae and Pinatubo oryzae; AGB27 had also good effect on Curvularia lunata and Bipolaris oryzae. However, all Bacillus gave immediate effect on Fusarium moniliforme.