The climate change is one of the global problems that affects human health and nature directly. Because of advantageous natural conditions, Artemia culture was studied and developed at Soc Trang – Bac Lieu coastal since 1980. However, under the climate change such as: early rainy season, water shortage, sudden change temperature,… caused unpredictable for Artemia farming.. Therefore, the survey was carried out by interviewing directly 60 households in 3 wards: Vinh Phuoc,  Vinh Tan (Soc Trang) and Lai Hoa (Bac Lieu) during April to May 2015 in order to study the awareness of Artemia farmers, to record any possible technical modification in Artemia culture techniques to deal with unusual weather. Besides that, the survey gives evaluation and strategic solution to adapt the effects of climate change through training, transfer technology between the universities, farmers and local government.