Article info.

ABSTRACT

Received 27 Dec 2017
Revised 09 Mar 2018

Accepted 30 Nov 2018

Iron-organic framework MOF-235 was synthesized from 1,4-benzenedicarboxylic acid and iron(III) chloride by a solvothermal method. Physical characterizations of the solid catalyst were achieved by using a variety of techniques. The  Fe-MOF was used as a productive heterogeneous catalyst for the synthesis of benzimidazoles via oxidative condensation of primary amines with 1,2-diaminoarenes.  The MOF-235 was found to be more catalytically active for the oxidative condensation of primary amines with 1,2-diaminoarenes than other Metal-organic frameworks (MOFs). Leaching tests verified that the cyclization of 1,2-phenylenediamine with benzylamine to generate 2-phenyl-1H-benzo[d]imidazole was only possible in the presence of the iron-based framework catalyst, thus indicating that the transformation progressed via truly heterogeneous catalysis.

Keywords

1,2-diaminoarenes, benzimidazoles, condensation, cyclization, MOF-235

Cited as: Tran, N.T.N., Hang, D.T., Thien, L.N., Giao, D.H. and Nam, P.T.S., 2018. Benzimidazole synthesis via oxidative condensation of 1,2-diaminoarenes with primary amines  using MOF-235 as an effective heterogeneous catalyst. Can Tho University Journal of Science. 54(8): 88-95.