Thirty five rabbit does were arranged in a completely randomized design with 5 treatments and 7 replications to evaluate the reproductive performance of crossbred rabbits fed 5 levels of crude protein (CP) including 30, 32, 34, 36 and 38g CP/doe/day corresponding to the CP30, CP32, CP34, CP36 and CP38 treatments. The crude protein supplementation in diets was come from water spinach leaves and concentrate with Para grass (Brachiariamutica) as a basal diet.The results showed that litter size at birth, weight of litter at birth, number of rabbit at weaning, weight of rabbit at weaning in litter1 enhanced with increasing of CP in the diets, the higher values were found for the treatments of 36 and 38g CP/doe/day (P>0.05). The growth rate of pregnant doe and milk production (g/doe/day) of experimental rabbits increased with increasing of CP levels in the diets and the values were higher for the treatments of 36 and 38g CP/doe/day (Pnumber of rabbit at weaning, weight of rabbit at weaning improved with increasing of CP levels in the diets (P(Preproductive performance in two litters were found in the 36 and 38g CP/doe/day diets.