The study aims to determine factors and the impact level of each factor on tax officials’ occupational stress in Binh Thuan Province. Research data were collected from 300 tax officials using convenient sampling. Applying the exploratory factor analysis and multivariate linear regression, the study has proven factors that increase occupational stress of tax officials. Accordingly, they are work nature and organizational characteristics. Otherwise, factors reducing their occupational stress are career development, the organization’s role, and tax officials’ commitments. In particular, commitment has the most influence on their occupational stress.