Đăng nhập
Tìm kiếm nâng cao
Tên bài báo
Tác giả
Năm xuất bản
Tóm tắt
Lĩnh vực
Phân loại
Số tạp chí

Bản tin định kỳ
Báo cáo thường niên
Tạp chí khoa học ĐHCT
Tạp chí tiếng anh ĐHCT
Tạp chí trong nước
Tạp chí quốc tế
Kỷ yếu HN trong nước
Kỷ yếu HN quốc tế
Book chapter
Tạp chí quốc tế 2015
Số tạp chí 308(2015) Trang: R907–R915
Tạp chí: Am J Physiol Regul Integr Comp Physiol

High affinity and temperature sensitivity of blood oxygen binding in Pangasianodon hypophthalmus due to lack of chloride- hemoglobin allosteric interaction. Am J Physiol Regul Integr Comp Physiol 308: R907–R915, 2015. First published March 25, 2015; doi:10.1152/ajpregu.00470.2014.—Air-breathing fishes represent in- teresting organisms in terms of understanding the physiological changes associated with the terrestrialization of vertebrates, and, further, are of great socio-economic importance for aquaculture in Southeast Asia. To understand how environmental factors, such as high temperature, affect O2 transport in air-breathing fishes, this study assessed the effects of temperature on O2 binding of blood and Hb in the economically important air-breathing fish Pangasianodon hypo- phthalmus. To determine blood O2 binding properties, blood was drawn from resting cannulated fishes and O2 binding curves made at 25°C and 35°C. To determine the allosteric regulation and thermody- namics of Hb O2 binding, Hb was purified, and O2 equilibria were recorded at five temperatures in the absence and presence of ATP and Cl. Whole blood had a high O2 affinity (O2 tension at half saturation P50 4.6 mmHg at extracellular pH 7.6 and 25°C), a high temper- ature sensitivity of O2 binding (apparent heat of oxygenation Happ 28.3 kcal/mol), and lacked a Root effect. Further, the data on Hb revealed weak ATP binding and a complete lack of Clbinding to Hb, which, in part, explains the high O2 affinity and high temperature sensitivity of blood O2 binding. This study demonstrates how a potent mechanism for increasing O2 affinity is linked to increased tempera- ture sensitivity of O2 transport and provides a basic framework for a better understanding of how hypoxia-adapted species will react to increasing temperatures. 

Các bài báo khác
Số tạp chí Volume 1, Number 1(2015) Trang: 55-62
Tạp chí: International Journal of Science Educators and Teachers
Số tạp chí 1(2015) Trang: 121-138
Tạp chí: Nonlinear Functional Analysis anh Applications
Số tạp chí DOI 10.1007/s00244-015-0182-3(2015) Trang:
Tạp chí: Archives of Environmental Contamination and Toxicology
Số tạp chí Volume 7, Issue 1(2015) Trang: 41-46
Tạp chí: International Aquatic Research
Số tạp chí Volume:30 , Issue: 2(2015) Trang: 578 - 587
Tạp chí: Energy Conversion, IEEE Transactions on
Số tạp chí Vol.15 No.2(2015) Trang: 411-418
Số tạp chí Volume:30 , Issue: 3(2015) Trang: 1126 - 1130
Tạp chí: Power Electronics, IEEE Transactions on
Số tạp chí 4(2015) Trang: 295-300
Tạp chí: International Journal of Research in Engineering and Technology
Số tạp chí 3(2015) Trang: 1164-1171
Tạp chí: International Journal of Science, Engineering and Technology ISSN: 2348-4098.

Vietnamese | English

Vui lòng chờ...