Study on cultivation of sea grape (Caulerpa lentiliifera) in the 1 m²- lined ponds, a 2×2 factorial experiment with two water levels (40 and 80 cm) and two water exchange rate (25% and 50%/week) was randomly designed in triplicate. Sea grape was cultivated at salinity of 30 ppt with continuous aeration, initial stocking rate of 1 kg /m² and fishmeal was used as nutrient source for sea grape, and cultivation lasted for 60 days. Results showed that a significant interaction effect (p0.05). Water level and water exchange rate did not affect morphometric frond properties (commercial frond length, ramuli density and ramuli size) and sensory properties. It can be suggested that cultivation of sea grape C. lentillifera at water level of 80 cm combined with 50% water exchange per week could be the appropriate factors to obtain highest growth rate (1.95%/day) and frond production (12.21 kg/m²).