In Vietnam, the legal regulations related to compensation for medical malpractice without proving fault do not seem to be as widely known as in other countries in the world. A no-fault compensation system allows patients to be compensated without proof of a provider’s fault or negligence. Acknowledging and applying no-fault compensation rules are very important in medical malpractice to protect the legitimate rights and interests of victims. Studying, comparing, and analyzing the regulations of Vietnamese no-fault compensation with the progressive ones in the world. Based on the results, the author will indicate the weakness in the legal of Vietnamese no-fault compensation rules and present appropriate recommendations.