Activation of the three pathways of the complement system generates the C5 convertase as a source of inspiration in formation of the membrane attack complex (MAC) on target-cell membranes. This complex is a multiprotein set assembled by sequential addition of complement components C5b, C6, C7, C8, and C9. Upon binding of C7 to C5b-6, the trimolecular C5b-7 complex undergoes a conformational transition and allows insertion of this complex into lipid membranes. In this study, over 800bp of the 5´-untranslated region of the porcine C7 was sequenced and analyzed in comparison with that of several mammalian animal species. It is of interest that the TATA-box, transcription start site, GATAA-box, and transcription factor sites/binding sites such as GATA, LEF1, NKX25, NKX22, EcR, Tal-1, AP-2α, SP1, IK1, STAT1 showed highly conserved among pig, human, cattle, dog, and/or mouse. Obtained ones provided basic data for further studies on pig breeds with good immune response.