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Kỷ yếu hội nghị quốc tế 2015
Số tạp chí Volume 84 of IPCBEE (2015), DOI: 10.7763/IPCBEE. 2015. V84. 16(2015) Trang: 95-100
Tạp chí: 2015 6th International Conference on Environmental Science and Technology, May 23, 2015 - May 25, 2015, , Singapore

Abstract. This study was conducted to investigate the bioactivities of extracts, isolation and identification the compounds from aerial parts of Tridax procumbens (T. procumbens). The standardized ethyl acetate extract from T. procumbens shown antibacterial activity against gram negative bacteria as Escherichia coli and Pseudomonas aeruginosa, while the petroleum ether extract did not shown antibacterial activity. Besides, antioxidant activity of ethyl acetate extract (IC50=0.52 mg/mL) is higher than petroleum ether extract (IC50=1.12 mg/mL). Additionally, the ethyl acetate extract resulted significant anti-inflammatory on mice paw edema at the concentration of 200 mg/kg. Moreover, ethyl acetate extract contains two isolated compounds, namely β-sitosterol-3-O-β-D-glucopyranoside (1) and 3′,5-dihydroxy-4′,3,6-trimethoxyflavone- 7-O-β-D-glucopyranoside (2), which were identified by 1H-NMR, 13C-NMR, Mass spectrometry. The pharmacological activities of ethyl acetate extract and their compounds indicated that T. procumbens is promising resource for pharmaceutical industry.
Keywords: Tridax procumbens, antibacterial, anti-inflammatory, antioxidant, daucosterol, centaurein.

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