The study contributes to the knowledge on growth and condition factor of the commercial fish Glossogobius sparsipapillus, based on the data analysis of 764 individuals (356 females and 408 males). Specimens were caught using gill nets in four sampling sites (Cai Rang, Can Tho to Long Phu, Soc Trang, Hoa Binh, Bac Lieu, and Dam Doi, Ca Mau) during the period from January 2020 to December 2020. The findings show that fish weights of females and males, for various sizes, seasons and sampling sites, can be estimated from the measured lengths, given the length-weight relationships (LWRs) with rather high determination coefficients. The species G. sparsipapillus showed a similar growth parameter (b) between genders and fish sizes, but not for seasons and sampling sites. As the b obtained from LWRs is lower than the three, this species displays a negative allometric growth and tends to face overexploitation. Although the condition factor (CF) shows intraspecific, seasonal, spatial and temporal changes, it still remains close to the favorable threshold of one, suggesting that the goby adapted well to the habitat. The results serve as a helpful reference to the fish biology, in support to the fish resources management.