An experiment was conducted to evaluate the effects of extracted β-glucan (BGD), an organic acid mixture (OAD) and a proprietary probiotic (PD) in diets on the performance and health status of weaning pigs from 4 to 10 weeks of age. Sixty crossbred castrated (Yorkshire x Landrace) male weaned pigs (mean live weight 7.0 ± 1.5 kg) were allocated to four treatments in a randomized complete block design. The pigs were allocated to 5 pens (replicates) with 3 pigs/pen. The control diet (CD) was based on broken rice, rice bran, maize meal, soybean meal and fish meal. For the experimental treatments the basal diet was supplemented with extracted β-glucan, an organic acid mixture (mainly fumaric acid, lactic acid, calcium formate and phosphoric acid) or a proprietary probiotic (providing Bacillus subtilis, Lactobacillus spp and Saccharomyces cerevisiae) at levels of 2g/kg, Daily live weight gain and feed conversion in recently weaned piglets were improved by all the supplements. In the 2 weeks post-weaning, the piglets supplemented with organic acids or with probiotic suffered less diarrhoea and had lower concentrations of E.coli in feces than pigs fed the control diet or that supplemented with β-glucan.